How to use System Explorer as Task Manager Replacement
This option is not available for 64bit operating systems and Windows7. BUT....You can still use System Explorer as Task Manager Replacement. Just use "CTRL+ALT+INS" hotkey instead of "CTRL+ALT+DEL".
it is however possible to replace the ctrl+shift+esc key combination.
Until this is directly supported, you can such functionality with an autohotkey script:
^+Esc::
run %a_programfiles%\SystemExplorer\SystemExplorer.exe
return